Table of Contents
Print

What Hormonal Factors Influence the Comorbidity of ADHD and Anxiety in Women? 

The hormonal factors that influence the comorbidity of ADHD and anxiety in women are significant and often underestimated. Research has shown that hormonal fluctuations, particularly in estrogen and progesterone levels throughout the menstrual cycle, can impact both ADHD and anxiety symptoms. These hormonal changes can make it more challenging for women to manage both conditions, with some experiencing exacerbated symptoms at certain times in their cycle. 

Hormonal Factors in ADHD and Anxiety 

Estrogen and progesterone have a profound effect on the brain’s neurotransmitter systems, which are key in regulating attention and mood. Throughout the menstrual cycle, hormonal factors such as changes in estrogen levels can influence mood, anxiety, and cognitive function. For example, estrogen levels are typically higher in the first half of the cycle, which may improve focus and mood. However, as estrogen drops during the second half of the cycle, many women with ADHD and anxiety experience worsened symptoms, such as increased inattention, impulsivity, and heightened anxiety. 

Menstrual Cycle, Estrogen, and Progesterone 

The menstrual cycle is a key factor that determines how hormonal factors affect ADHD and anxiety symptoms. When progesterone rises and estrogen declines in the premenstrual phase, women may experience increased anxiety, irritability, and trouble concentrating. These changes can intensify both ADHD and anxiety symptoms, making it harder to manage daily tasks. Additionally, progesterone is known to have calming effects, but higher levels can also lead to emotional swings, further complicating the management of these conditions. 

Key Hormonal Factors in ADHD and Anxiety in Women 

Hormonal Factors 

Fluctuations in hormonal factors like estrogen and progesterone can significantly affect the severity of ADHD and anxiety in women. 

Menstrual Cycle 

 The menstrual cycle plays a critical role in how hormonal factors impact ADHD and anxiety symptoms, particularly during the premenstrual phase. 

Estrogen and Progesterone 

The balance between estrogen and progesterone influences mood, attention, and emotional regulation, making them key hormonal factors in the management of ADHD and anxiety. 

For personal consultations on ADHD and anxiety, visit providers like ADHD Certify. For a deeper dive into the science, diagnosis, and full treatment landscape, read our complete guide to Anxiety disorders.

Dr. Rebecca Fernandez, MBBS, author and a reviewer for my patient advice - mypatientadvice.co.uk

Dr. Rebecca Fernandez, MBBS

Author

Dr. Rebecca Fernandez is a UK-trained physician with an MBBS and experience in general surgery, cardiology, internal medicine, gynecology, intensive care, and emergency medicine. She has managed critically ill patients, stabilised acute trauma cases, and provided comprehensive inpatient and outpatient care. In psychiatry, Dr. Fernandez has worked with psychotic, mood, anxiety, and substance use disorders, applying evidence-based approaches such as CBT, ACT, and mindfulness-based therapies. Her skills span patient assessment, treatment planning, and the integration of digital health solutions to support mental well-being.

All qualifications and professional experience stated above are authentic and verified by our editorial team. However, pseudonym and image likeness are used to protect the author's privacy.