Does PCB Exposure During Pregnancy Contribute to Autism Risk? 

Research suggests that PCBs and autism may be linked, with prenatal exposure to polychlorinated biphenyls (PCBs) potentially increasing the risk of autism spectrum disorders (ASD). PCBs and autism are a growing concern because PCBs, classified as persistent organic pollutants, remain in the environment for decades and accumulate in the human body, where they can interfere with brain development. 

PCBs and autism are connected through their ability to cross the placenta during pregnancy. This prenatal exposure may disrupt critical neurodevelopmental processes, such as neurotransmitter function and hormone regulation, both essential for healthy brain growth. 

How Do PCBs Affect Autism Risk? 

Understanding the impact of PCBs and autism is key to recognising environmental risk factors. Here’s how persistent organic pollutants like PCBs can influence neurodevelopment: 

Prenatal Exposure:  

Maternal exposure to PCBs during pregnancy allows these chemicals to cross the placenta and reach the developing foetus. This prenatal exposure can impair brain development, increasing the risk of autism and other developmental delays. 

Long-Term Effects:  

Children exposed to PCBs and autism risk factors may face difficulties with learning, communication, and social interaction. Because PCBs are persistent organic pollutants, they accumulate in the body and environment, compounding developmental risks over time. 

Visit providers like Autism Detect for personal consultations to understand how PCBs and autism may affect your child’s development and explore strategies to reduce exposure to harmful chemicals. 

For a deeper dive into the science, diagnosis, and full treatment landscape, read our complete guide to Exposure to Toxins or Pollutants.

Hannah Smith, MSc

Author

Hannah Smith is a clinical psychologist with a Master’s in Clinical Psychology and over three years of experience in behaviour therapy, special education, and inclusive practices. She specialises in Applied Behavior Analysis (ABA), Cognitive Behavioural Therapy (CBT), and inclusive education strategies. Hannah has worked extensively with children and adults with Autism Spectrum Disorder (ASD), ADHD, Down syndrome, and intellectual disabilities, delivering evidence-based interventions to support development, mental health, and well-being.

All qualifications and professional experience stated above are authentic and verified by our editorial team. However, pseudonym and image likeness are used to protect the author's privacy. 

Dr. Rebecca Fernandez, MBBS

Reviewer

Dr. Rebecca Fernandez is a UK-trained physician with an MBBS and experience in general surgery, cardiology, internal medicine, gynecology, intensive care, and emergency medicine. She has managed critically ill patients, stabilised acute trauma cases, and provided comprehensive inpatient and outpatient care. In psychiatry, Dr. Fernandez has worked with psychotic, mood, anxiety, and substance use disorders, applying evidence-based approaches such as CBT, ACT, and mindfulness-based therapies. Her skills span patient assessment, treatment planning, and the integration of digital health solutions to support mental well-being.

All qualifications and professional experience stated above are authentic and verified by our editorial team. However, pseudonym and image likeness are used to protect the reviewer's privacy.