Does maternal exposure to endocrine-disrupting chemicals during pregnancy affect autism risk?

PostedNovember 30, 2025

UpdatedNovember 30, 2025

ByMy Patient Advice

Author: Hannah Smith, MSc | Reviewed by: Dr. Rebecca Fernandez, MBBS

The connection between maternal exposure to endocrine-disrupting chemicals and autism is becoming a growing concern among researchers. These chemicals, found in everyday items like plastics, pesticides, and personal care products, can interfere with natural hormone activity, potentially impacting brain development during pregnancy.

When maternal exposure to endocrine-disrupting chemicals and autism is studied, a key mechanism identified is hormone disruption. These chemicals can mimic or block hormones critical to regulating growth and brain function in the foetus. As a result, exposure to prenatal toxins may contribute to altered neural development and an increased likelihood of autism spectrum disorder (ASD).

Research suggests that the risk intensifies when hormone disruption occurs during the first trimester, when the brain is forming rapidly. Reducing exposure to prenatal toxins such as BPA, phthalates, and certain flame retardants may help protect neurological pathways and lower potential risks. As understanding deepens around maternal exposure to endocrine-disrupting chemicals and autism, more emphasis is being placed on informed choices during pregnancy.

Developmental Differences That May Arise

If prenatal brain development is affected, these signs may appear early in life:

Oversensitivity to Sensory Input

Loud sounds, strong smells, or tactile input may cause distress. Sensory-based therapies help children process and respond more comfortably.

Repetitive Use of Language or Objects

Children may echo phrases or use objects in a fixed, repetitive way. Behavioural therapy supports more flexible communication and play.

Limited Interest in Social Play

A child may prefer solitary activities or struggle with peer interaction. Structured social programmes can build connection and confidence.

Visit providers like Autism Detect for personal consultations to understand how maternal health and sensory processing impact your child’s development and how to support effective sensory regulation and comfort.

For a deeper dive into the science, diagnosis, and full treatment landscape, read our complete guide to Maternal Health and Infections.

Hannah Smith, MSc

Author

Hannah Smith is a clinical psychologist with a Master’s in Clinical Psychology and over three years of experience in behaviour therapy, special education, and inclusive practices. She specialises in Applied Behavior Analysis (ABA), Cognitive Behavioural Therapy (CBT), and inclusive education strategies. Hannah has worked extensively with children and adults with Autism Spectrum Disorder (ASD), ADHD, Down syndrome, and intellectual disabilities, delivering evidence-based interventions to support development, mental health, and well-being.

All qualifications and professional experience stated above are authentic and verified by our editorial team. However, pseudonym and image likeness are used to protect the author's privacy.

Dr. Rebecca Fernandez, MBBS

Reviewer

Dr. Rebecca Fernandez is a UK-trained physician with an MBBS and experience in general surgery, cardiology, internal medicine, gynecology, intensive care, and emergency medicine. She has managed critically ill patients, stabilised acute trauma cases, and provided comprehensive inpatient and outpatient care. In psychiatry, Dr. Fernandez has worked with psychotic, mood, anxiety, and substance use disorders, applying evidence-based approaches such as CBT, ACT, and mindfulness-based therapies. Her skills span patient assessment, treatment planning, and the integration of digital health solutions to support mental well-being.

All qualifications and professional experience stated above are authentic and verified by our editorial team. However, pseudonym and image likeness are used to protect the reviewer's privacy.