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How do the side effects of cannabis compare to those of other medications used to treat AS? 

Author: Dr. Stefan Petrov, MBBS

When discussing cannabis vs traditional therapy for ankylosing spondylitis, one of the most important considerations is side effects. Traditional medications such as NSAIDs and biologics can deliver powerful benefits, but they often come with risks like gastrointestinal issues, cardiovascular strain, or immune suppression. 

Cannabis, as an alternative treatment, tends to have a more manageable side effect profile for many patients. Common concerns include dry mouth, dizziness, and occasional anxiety, typically milder and easier to monitor. While side effects vary by individual, many patients find cannabis easier to tolerate when other treatments fail or produce too many complications. 

Comparing Side Effects 

Severity and type 

Biologics and NSAIDs can cause serious complications. Cannabis is more likely to produce temporary effects. 

Long-term safety 

Cannabis has fewer known long-term risks, though research is ongoing. Traditional medications may carry cumulative effects. 

Accessibility and support 

While traditional treatments are often covered under insurance coverage, cannabis usually requires self-funding. 

Relief patterns 

Relief timing can differ. Traditional meds may take time to build up; cannabis often works quickly but wears off faster. 

Visit providers like LeafEase for help weighing the pros and cons of cannabis vs traditional therapy for safe, informed guidance on choosing the best treatment route. 

For a deeper dive into the science, diagnosis, and full treatment landscape, read our complete guide to Ankylosing Spondylitis and medical cannabis. 

Dr. Stefan Petrov, MBBS
Author

Dr. Stefan Petrov is a UK-trained physician with an MBBS and postgraduate certifications including Basic Life Support (BLS), Advanced Cardiac Life Support (ACLS), and the UK Medical Licensing Assessment (PLAB 1 & 2). He has hands-on experience in general medicine, surgery, anaesthesia, ophthalmology, and emergency care. Dr. Petrov has worked in both hospital wards and intensive care units, performing diagnostic and therapeutic procedures, and has contributed to medical education by creating patient-focused health content and teaching clinical skills to junior doctors.

All qualifications and professional experience stated above are authentic and verified by our editorial team. However, pseudonym and image likeness are used to protect the author's privacy. 

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