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Are ADHD Screening Tools Sensitive to Comorbid Depression? 

PostedSeptember 3, 2025
UpdatedSeptember 3, 2025
ByMy Patient Advice

The effectiveness of ADHD screening tools comorbid with depression is an important area of discussion in mental health assessment. Many individuals present with overlapping symptoms, such as poor concentration, low energy and irritability, which are common to both ADHD and depression. This can make it challenging for screening instruments to accurately identify ADHD when depression is also present. 

The accuracy of these tools often depends on their sensitivity and specificity. High sensitivity ensures that most individuals with ADHD are correctly identified, even if depression is also present, while high specificity reduces the likelihood of false positives. However, when symptoms from both conditions overlap, test accuracy may be affected, leading to potential underdiagnosis or misdiagnosis. 

How Comorbidity Affects Screening 

Symptom overlap 

Both ADHD and depression share issues with focus, motivation and emotional regulation, which can complicate screening results. 

Impact on sensitivity and specificity 

Comorbid depression can reduce the precision of ADHD screening tools comorbid, affecting their ability to differentiate between the two conditions. 

Need for thorough assessment 

To improve test accuracy, screening should be combined with detailed clinical interviews, history-taking and collateral reports from family or teachers. 

Recognising the limitations of ADHD screening tools comorbid with depression is vital for improving diagnostic outcomes and ensuring individuals receive appropriate treatment for both conditions. 

Visit providers like ADHD Certify for personal consultations and expert advice tailored to your needs.   

For a deeper dive into the science, diagnosis, and full treatment landscape, read our complete guide to Depression.  

Harriet Winslow, BSc - My patient advice author - mypatientadvice.co.uk

Harriet Winslow, BSc

Author

Harriet Winslow is a clinical psychologist with a Bachelor’s in Clinical Psychology and extensive experience in behaviour therapy and developmental disorders. She has worked with children and adolescents with ADHD, autism spectrum disorder (ASD), learning disabilities, and behavioural challenges, providing individual and group therapy using evidence-based approaches such as CBT and DBT. Dr. Winslow has developed and implemented personalised treatment plans, conducted formal and informal assessments, and delivered crisis intervention for clients in need of urgent mental health care. Her expertise spans assessment, treatment planning, and behavioural intervention for both neurodevelopmental and mental health conditions.

All qualifications and professional experience stated above are authentic and verified by our editorial team. However, pseudonym and image likeness are used to protect the author's privacy.

Dr. Rebecca Fernandez, MBBS, author and a reviewer for my patient advice - mypatientadvice.co.uk

Dr. Rebecca Fernandez, MBBS

Reviewer

Dr. Rebecca Fernandez is a UK-trained physician with an MBBS and experience in general surgery, cardiology, internal medicine, gynecology, intensive care, and emergency medicine. She has managed critically ill patients, stabilised acute trauma cases, and provided comprehensive inpatient and outpatient care. In psychiatry, Dr. Fernandez has worked with psychotic, mood, anxiety, and substance use disorders, applying evidence-based approaches such as CBT, ACT, and mindfulness-based therapies. Her skills span patient assessment, treatment planning, and the integration of digital health solutions to support mental well-being.

All qualifications and professional experience stated above are authentic and verified by our editorial team. However, pseudonym and image likeness are used to protect the reviewer's privacy. 

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