my patient advice logo - used for header - mypatientadvice.co.uk
All Topics
Contact Us
Free Health Updates
Table of Contents
< All Topics
Print

Does AuDHD Increase Depression Risk? 

PostedSeptember 18, 2025
UpdatedSeptember 18, 2025
ByMy Patient Advice

Yes, depression risk can be higher for individuals with AuDHD, a term used to describe the co-occurrence of autism (ASD) and attention deficit hyperactivity disorder (ADHD).The challenges that come with managing both conditions, including social difficulties, sensory sensitivities, and struggles with focus, can create a greater risk of developing depression. For individuals with autism and ADHD, the combination of these factors can lead to feelings of isolation, frustration, and hopelessness, which significantly impact mental health. 

The depression, autism ADHD overlap often means that individuals may feel misunderstood or unable to meet societal expectations, contributing to low self-esteem and mental health struggles. As a result, it is important to understand the connection between AuDHD and depression to identify early warning signs and provide appropriate support. 

Schedule your ADHD assessment

How AuDHD Increases Depression Risk 

Here are some key factors that can increase the depression risk in AuDHD: 

Social Isolation and Difficulty with Relationships  

Adults with AuDHD may find it difficult to form and maintain relationships, due to both social communication challenges from autism and impulsive behaviours from ADHD. This isolation can lead to feelings of loneliness and increase the risk of depression. Therapy, including Cognitive Behavioural Therapy (CBT), can help individuals develop social skills and improve relationship-building, reducing feelings of isolation and addressing depressive symptoms. 

Chronic Stress from Sensory Overload  

AuDHD individuals often experience heightened sensory sensitivity, which can lead to chronic stress. Over time, this constant overstimulation can lead to emotional burnout, exacerbating feelings of sadness and hopelessness, which are core symptoms of depression. Mindfulness techniques and sensory integration therapies can help reduce the impact of sensory overload, leading to better emotional regulation and lower levels of depression. 

If you are concerned about depression risk related to AuDHD, visit providers like ADHD Certify for guidance on managing mental health and finding appropriate support.

For a deeper dive into the science, diagnosis, and full treatment landscape, read our complete guide to Autism Spectrum Disorder.

Schedule your ADHD assessment
Victoria Rowe, MSc, author for my patient advice - mypatientadvice.co.uk

Victoria Rowe, MSc

Author

Victoria Rowe is a health psychologist with a Master’s in Health Psychology and a BS in Applied Psychology. She has experience as a school psychologist, conducting behavioural assessments, developing individualized education plans (IEPs), and supporting children’s mental health. Dr. Rowe has contributed to peer-reviewed research on mental health, including studies on anxiety disorders and the impact of COVID-19 on healthcare systems. Skilled in SPSS, Minitab, and academic writing, she is committed to advancing psychological knowledge and promoting well-being through evidence-based practice.

All qualifications and professional experience stated above are authentic and verified by our editorial team. However, pseudonym and image likeness are used to protect the author's privacy. 

Dr. Rebecca Fernandez, MBBS, author and a reviewer for my patient advice - mypatientadvice.co.uk

Dr. Rebecca Fernandez, MBBS

Reviewer

Dr. Rebecca Fernandez is a UK-trained physician with an MBBS and experience in general surgery, cardiology, internal medicine, gynecology, intensive care, and emergency medicine. She has managed critically ill patients, stabilised acute trauma cases, and provided comprehensive inpatient and outpatient care. In psychiatry, Dr. Fernandez has worked with psychotic, mood, anxiety, and substance use disorders, applying evidence-based approaches such as CBT, ACT, and mindfulness-based therapies. Her skills span patient assessment, treatment planning, and the integration of digital health solutions to support mental well-being.

All qualifications and professional experience stated above are authentic and verified by our editorial team. However, pseudonym and image likeness are used to protect the reviewer's privacy. 

Let’s get started on something great

Sign Up for our FREE monthly medical updates. No spamming! Only the best content summary from the month on all medical topics

© 2025 My Patient Advice. All rights reserved.