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What Non-Stimulant Meds Suit AuDHD? 

Non-stimulant meds AuDHD are an important treatment consideration for individuals with both autism and ADHD. Although stimulant medications are usually the first choice for treating ADHD, they may not be suitable for everyone especially those with  AuDHD, where sensory sensitivities, anxiety, or side effects can make stimulants harder to to tolerate. In such cases, autism med options that include non-stimulant medications can offer a more balanced approach to symptom management. 

Non-stimulant medications can help improve focus, reduce impulsivity, and support emotional regulation without some of the common side effects associated with stimulants, such as increased anxiety, appetite loss, or sleep disturbances. For individuals with AuDHD, this can make them a valuable part of a tailored treatment plan. 

Common Non-Stimulant Medications for AuDHD 

Common non-stimulant medications for AuDHD include atomoxetine, guanfacine, and clonidine, which can help manage attention and behaviour. 

Atomoxetine (Strattera)  

It is one of the most widely prescribed non-stimulant meds for ADHD, atomoxetine works by increasing norepinephrine levels in the brain, which helps improve attention and reduce impulsivity. For individuals with AuDHD, atomoxetine can be effective without the heightened sensory or anxiety-related side effects sometimes caused by stimulants. It is also taken once daily, which may be easier for those who struggle with medication routines. 

Guanfacine (Intuniv) and Clonidine (Kapvay)  

This was originally developed for high blood pressure; these medications are now used to treat ADHD symptoms by calming overactive brain signals. For individuals with AuDHD, guanfacine and clonidine can help manage hyperactivity, impulsivity, and emotional dysregulation, while also reducing anxiety. These autism med options can be particularly beneficial for those who experience overstimulation or difficulty sleeping. 

Antidepressants (e.g., Bupropion) While not officially approved for ADHD, certain antidepressants like bupropion can help with focus, motivation, and mood regulation. They may be considered for individuals with AuDHD who also experience depression or anxiety alongside attention-related difficulties. 

Choosing the right non-stimulant meds for AuDHD requires careful consideration of an individual’s unique symptoms, sensitivities, and co-occurring conditions. Working closely with a healthcare provider ensures the most effective and tolerable treatment plan. 

For expert advice on ADHD medication and autism med options, providers like ADHD Certify can offer tailored guidance.

For a deeper dive into the science, diagnosis, and full treatment landscape, read our complete guide to Autism Spectrum Disorder.

Victoria Rowe, MSc, author for my patient advice - mypatientadvice.co.uk

Victoria Rowe, MSc

Author

Victoria Rowe is a health psychologist with a Master’s in Health Psychology and a BS in Applied Psychology. She has experience as a school psychologist, conducting behavioural assessments, developing individualized education plans (IEPs), and supporting children’s mental health. Dr. Rowe has contributed to peer-reviewed research on mental health, including studies on anxiety disorders and the impact of COVID-19 on healthcare systems. Skilled in SPSS, Minitab, and academic writing, she is committed to advancing psychological knowledge and promoting well-being through evidence-based practice.

All qualifications and professional experience stated above are authentic and verified by our editorial team. However, pseudonym and image likeness are used to protect the author's privacy. 

Dr. Rebecca Fernandez, MBBS, author and a reviewer for my patient advice - mypatientadvice.co.uk

Dr. Rebecca Fernandez, MBBS

Reviewer

Dr. Rebecca Fernandez is a UK-trained physician with an MBBS and experience in general surgery, cardiology, internal medicine, gynecology, intensive care, and emergency medicine. She has managed critically ill patients, stabilised acute trauma cases, and provided comprehensive inpatient and outpatient care. In psychiatry, Dr. Fernandez has worked with psychotic, mood, anxiety, and substance use disorders, applying evidence-based approaches such as CBT, ACT, and mindfulness-based therapies. Her skills span patient assessment, treatment planning, and the integration of digital health solutions to support mental well-being.

All qualifications and professional experience stated above are authentic and verified by our editorial team. However, pseudonym and image likeness are used to protect the reviewer's privacy.