What are common side effects of medications used for hyperactivity in ADHD?

PostedAugust 22, 2025

UpdatedSeptember 5, 2025

ByMy Patient Advice

Author: Victoria Rowe, MSc | Reviewed by: Dr. Rebecca Fernandez, MBBS

While medication is often effective at managing symptoms, it is important to understand the potential side effects of drugs prescribed for hyperactivity in ADHD. Knowing what to expect helps individuals and families weigh the benefits against the risks and make informed choices.

Most hyperactivity meds, particularly stimulants, are generally safe when taken as directed, but they can cause some uncomfortable reactions. Being aware of ADHD medication risks and working closely with a clinician ensures any problems are addressed promptly.

Common Side Effects to Watch For

Here are some typical stimulant reactions and other side effects people may experience when taking medication for ADHD:

Insomnia

Trouble falling or staying asleep is a common side effect, particularly when medication is taken later in the day. Adjusting the dose or timing can often resolve this issue.

Decreased Appetite and Weight Loss

Stimulants can reduce hunger, sometimes leading to weight loss. Eating nutrient-dense meals and monitoring weight can mitigate this issue.

Increased Heart Rate or Blood Pressure

Some people experience mild cardiovascular effects, which should be monitored by a healthcare provider.

Mood Changes or Irritability

Occasionally, medications can cause emotional ups and downs. If this occurs, the clinician may adjust the dose or try an alternative.

By understanding these ADHD medication risks, you can work with your clinician to find the right balance between symptom control and side effects. Visit providers like ADHD Certify for personal consultations and advice tailored to your needs.

For a deeper dive into the science, diagnosis, and full treatment landscape, read our complete guide to Hyperactivity.

Victoria Rowe, MSc

Author

Victoria Rowe is a health psychologist with a Master’s in Health Psychology and a BS in Applied Psychology. She has experience as a school psychologist, conducting behavioural assessments, developing individualized education plans (IEPs), and supporting children’s mental health. Dr. Rowe has contributed to peer-reviewed research on mental health, including studies on anxiety disorders and the impact of COVID-19 on healthcare systems. Skilled in SPSS, Minitab, and academic writing, she is committed to advancing psychological knowledge and promoting well-being through evidence-based practice.

All qualifications and professional experience stated above are authentic and verified by our editorial team. However, pseudonym and image likeness are used to protect the author's privacy.

Dr. Rebecca Fernandez, MBBS

Reviewer

Dr. Rebecca Fernandez is a UK-trained physician with an MBBS and experience in general surgery, cardiology, internal medicine, gynecology, intensive care, and emergency medicine. She has managed critically ill patients, stabilised acute trauma cases, and provided comprehensive inpatient and outpatient care. In psychiatry, Dr. Fernandez has worked with psychotic, mood, anxiety, and substance use disorders, applying evidence-based approaches such as CBT, ACT, and mindfulness-based therapies. Her skills span patient assessment, treatment planning, and the integration of digital health solutions to support mental well-being.

All qualifications and professional experience stated above are authentic and verified by our editorial team. However, pseudonym and image likeness are used to protect the reviewer's privacy.