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Can Brain Structure and Function Abnormalities from Prenatal Factors Contribute to ADHD? 

PostedAugust 18, 2025
UpdatedSeptember 4, 2025
ByMy Patient Advice

Brain structure and function abnormalities caused by prenatal factors can significantly contribute to brain structure ADHD , influencing a child’s neurodevelopment and behaviour. When certain prenatal risks, such as maternal stress, infections, or substance abuse, affect the developing brain, they can lead to lasting changes in the areas responsible for attention, impulse control, and emotional regulation. These abnormalities are strongly linked to ADHD behaviour, particularly in children with a history of prenatal complications. 

Studies have shown that changes in brain structure ADHD can be identified in ADHD in children through imaging techniques. These scans often reveal structural differences in regions like the prefrontal cortex, which is crucial for executive function, decision-making, and behavioural control. When these areas are impacted during prenatal development, children may experience difficulties with neurodevelopment, resulting in challenges with focus, self-regulation, and organisation. 

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Common Symptoms of ADHD Linked to Prenatal Brain Abnormalities 

Children with prenatal brain structure abnormalities may display symptoms that reflect the changes in their brain development. Some common symptoms include: 

Inattention

These children often struggle to maintain focus on tasks, becoming easily distracted or forgetting instructions. They may find it challenging to complete assignments or stay organised, which can affect their academic performance and daily activities. 

Impulsivity

Children with ADHD may act without thinking, interrupt others, or have difficulty waiting their turn. These impulsive behaviours can lead to difficulties in social settings and classroom environments. 

Emotional Regulation Issues

Prenatal brain abnormalities can affect a child’s ability to regulate their emotions. Children may exhibit mood swings, frustration, or anger that seem disproportionate to the situation. 

Visit providers like ADHD Certify for personal consultations and expert advice tailored to your needs.   

For a deeper dive into the science, diagnosis, and full treatment landscape, read our complete guide to Brain Structure and Function.  

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Harriet Winslow, BSc - My patient advice author - mypatientadvice.co.uk

Harriet Winslow, BSc

Author

Harriet Winslow is a clinical psychologist with a Bachelor’s in Clinical Psychology and extensive experience in behaviour therapy and developmental disorders. She has worked with children and adolescents with ADHD, autism spectrum disorder (ASD), learning disabilities, and behavioural challenges, providing individual and group therapy using evidence-based approaches such as CBT and DBT. Dr. Winslow has developed and implemented personalised treatment plans, conducted formal and informal assessments, and delivered crisis intervention for clients in need of urgent mental health care. Her expertise spans assessment, treatment planning, and behavioural intervention for both neurodevelopmental and mental health conditions.

All qualifications and professional experience stated above are authentic and verified by our editorial team. However, pseudonym and image likeness are used to protect the author's privacy.

Dr. Rebecca Fernandez, MBBS, author and a reviewer for my patient advice - mypatientadvice.co.uk

Dr. Rebecca Fernandez, MBBS

Reviewer

Dr. Rebecca Fernandez is a UK-trained physician with an MBBS and experience in general surgery, cardiology, internal medicine, gynecology, intensive care, and emergency medicine. She has managed critically ill patients, stabilised acute trauma cases, and provided comprehensive inpatient and outpatient care. In psychiatry, Dr. Fernandez has worked with psychotic, mood, anxiety, and substance use disorders, applying evidence-based approaches such as CBT, ACT, and mindfulness-based therapies. Her skills span patient assessment, treatment planning, and the integration of digital health solutions to support mental well-being.

All qualifications and professional experience stated above are authentic and verified by our editorial team. However, pseudonym and image likeness are used to protect the reviewer's privacy. 

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