Does Family History of Only First-Degree Relatives Count for Inherited Autism?

PostedNovember 21, 2025

UpdatedNovember 21, 2025

ByMy Patient Advice

Author: Beatrice Holloway, MSc | Reviewed by: Dr. Rebecca Fernandez, MBBS

When considering first-degree relatives’ autism, many wonder if a family history of autism in immediate family members such as parents and siblings can play a significant role in the likelihood of inheriting the condition. Research indicates that genetics plays a crucial role in the development of autism, with first-degree relatives being particularly relevant in understanding the genetic links to autism.

The Importance of Relatives in Autism Inheritance

Parents, siblings, and children are closely related genetically and are the most likely to pass on traits related to autism. Studies show that individuals with a sibling or parent diagnosed with autism are more likely to show signs or even be diagnosed themselves. The risk is particularly elevated when the family history includes multiple relatives with autism, as it suggests a stronger genetic component.

However, it’s important to note that autism diagnosis can also be influenced by environmental factors and other genetic variations, so the presence of autism in first-degree relatives alone does not guarantee the inheritance of the condition.

Some common traits in individuals with autism, include:

Social difficulties

like challenges in communication or forming relationships.

Repetitive behaviours

such as hand-flapping or insistence on routines.

Sensory sensitivities

where an individual may react strongly to sounds, textures, or lights.

For treatment, CBT (Cognitive Behavioural Therapy) can help manage social and communication challenges, while medication may assist in managing sensory overload and repetitive behaviours.

Visit providers like Autism Detect for personal consultations to better understand how certain family traits from first degree relatives can impact autism risk.

For a deeper dive into the science, diagnosis, and full treatment landscape, read our complete guide to inherited traits and family history.

Beatrice Holloway, MSc

Author

Beatrice Holloway is a clinical psychologist with a Master’s in Clinical Psychology and a BS in Applied Psychology. She specialises in CBT, psychological testing, and applied behaviour therapy, working with children with autism spectrum disorder (ASD), developmental delays, and learning disabilities, as well as adults with bipolar disorder, schizophrenia, anxiety, OCD, and substance use disorders. Holloway creates personalised treatment plans to support emotional regulation, social skills, and academic progress in children, and delivers evidence-based therapy to improve mental health and well-being across all ages.

All qualifications and professional experience stated above are authentic and verified by our editorial team. However, pseudonym and image likeness are used to protect the author's privacy.

Dr. Rebecca Fernandez, MBBS

Reviewer

Dr. Rebecca Fernandez is a UK-trained physician with an MBBS and experience in general surgery, cardiology, internal medicine, gynecology, intensive care, and emergency medicine. She has managed critically ill patients, stabilised acute trauma cases, and provided comprehensive inpatient and outpatient care. In psychiatry, Dr. Fernandez has worked with psychotic, mood, anxiety, and substance use disorders, applying evidence-based approaches such as CBT, ACT, and mindfulness-based therapies. Her skills span patient assessment, treatment planning, and the integration of digital health solutions to support mental well-being.

All qualifications and professional experience stated above are authentic and verified by our editorial team. However, pseudonym and image likeness are used to protect the reviewer's privacy.