Can maternal exposure to endocrine-disrupting chemicals influence autism risk?

PostedNovember 30, 2025

UpdatedNovember 30, 2025

ByMy Patient Advice

Author: Hannah Smith, MSc | Reviewed by: Dr. Rebecca Fernandez, MBBS

New research is shedding light on the connection between maternal endocrine disruptors and autism. These chemicals, found in everyday items like plastics, pesticides, and cosmetics, can interfere with hormonal signals during pregnancy. Disrupting that balance may alter how the baby’s brain develops, increasing the risk of neurodevelopmental conditions such as autism spectrum disorder (ASD).

Scientists have found that maternal endocrine disruptors and autism are most strongly linked when exposure happens during the first trimester. During this period, prenatal hormones are guiding the formation of brain cells, wiring, and communication pathways. Even low levels of chemical exposure during pregnancy may disrupt this process, especially when combined with other risk factors.

While more research is needed, the growing body of evidence around maternal endocrine disruptors and autism points to prevention strategies. These include choosing glass over plastic, checking labels on personal care products, and being cautious around household pesticides, small steps that may help support balanced prenatal hormones and reduce chemical exposure during pregnancy.

What to Watch For: Developmental Behaviours

Autism shows up differently in every child. Here are a few behaviours that may signal the need for a closer look:

Lack of Back-and-Forth Interaction

Children may not mimic gestures, take turns in play, or respond to smiles. Early intervention can encourage social engagement and responsiveness.

Repetitive or Highly Focused Play

A child might spin objects or insist on using toys in only one way. Play therapy and CBT can help introduce flexibility and reduce anxiety-driven repetition.

Avoidance of Eye Contact or Facial Expressions

Some children avoid looking at others or may not read facial cues. Targeted social skills therapy can support emotional recognition and bonding.

Visit providers like Autism Detect for personal consultations to understand how maternal health and sensory processing impact your child’s development and how to support effective sensory regulation and comfort.

For a deeper dive into the science, diagnosis, and full treatment landscape, read our complete guide to Maternal Health and Infections.

Hannah Smith, MSc

Author

Hannah Smith is a clinical psychologist with a Master’s in Clinical Psychology and over three years of experience in behaviour therapy, special education, and inclusive practices. She specialises in Applied Behavior Analysis (ABA), Cognitive Behavioural Therapy (CBT), and inclusive education strategies. Hannah has worked extensively with children and adults with Autism Spectrum Disorder (ASD), ADHD, Down syndrome, and intellectual disabilities, delivering evidence-based interventions to support development, mental health, and well-being.

All qualifications and professional experience stated above are authentic and verified by our editorial team. However, pseudonym and image likeness are used to protect the author's privacy.

Dr. Rebecca Fernandez, MBBS

Reviewer

Dr. Rebecca Fernandez is a UK-trained physician with an MBBS and experience in general surgery, cardiology, internal medicine, gynecology, intensive care, and emergency medicine. She has managed critically ill patients, stabilised acute trauma cases, and provided comprehensive inpatient and outpatient care. In psychiatry, Dr. Fernandez has worked with psychotic, mood, anxiety, and substance use disorders, applying evidence-based approaches such as CBT, ACT, and mindfulness-based therapies. Her skills span patient assessment, treatment planning, and the integration of digital health solutions to support mental well-being.

All qualifications and professional experience stated above are authentic and verified by our editorial team. However, pseudonym and image likeness are used to protect the reviewer's privacy.