How Does the Endocannabinoid System Relate to Arthritis Pain?Â
The endocannabinoid system (ECS), a naturally occurring regulatory system in the body, helps in maintaining equilibrium among bodily processes such as inflammation, mood, and pain. Medical cannabis works by interacting with this system. This system seems to play a role in arthritis (3*), a disease characterised by chronic pain and inflammation of the joints. Cannabinoids, the active ingredients in cannabis, may aid in regulating these processes, according to early studies. This is one of the reasons why medical cannabis is being investigated in the UK to treat arthritis pain.
What Is the Endocannabinoid System?
Since CB2 receptors are present in immune cells and joint tissues, they are particularly pertinent when talking about the endocannabinoid system and arthritis.
The ECS is made up of cannabinoid receptors (mainly CB1 and CB2), the body’s natural endocannabinoids, and enzymes that break them down. It is essential for regulating pain, immune response, inflammation, and even sleep.
CB2 receptors are particularly important when talking about the endocannabinoid system and arthritis because they are present in immune cells and joint tissues.
How the Endocannabinoid System Affects Arthritis Symptoms
In arthritis, swelling, stiffness, and chronic pain are caused by inflammation around the joints. CBD receptors are found in the immune system and joints; activating these receptors (via cannabinoids like CBD or THC) may reduce inflammation and pain signalling.
This interaction is why research on the connection between CBD and arthritis pain is still ongoing. Cannabis-based medicines, such as Epidyolex (CBD) and Sativex (a THC: CBD blend), are being researched for their potential to treat joint disorders and are currently being used for specific conditions.
Explore how medical cannabis may help arthritis on our website when available (1*)
Thinking About Medical Cannabis?
The ECS is a promising target for managing arthritis pain, but results differ from patient to patient. Products with high levels of CBD strains are preferred because they may reduce inflammation without having strong psychoactive effects.
In the UK, medical cannabis is only available with a prescription and can only be legally acquired from a qualified healthcare professional. AlleviMed links patients with registered medical professionals who have experience writing prescriptions for medical cannabis to treat ailments like arthritis.
Learn more or book a medical cannabis consultation at LeafEaseÂ
