← All Topics

Which painkillers are safe after a concussion head injury? 

Following a concussion or minor head injury, the most appropriate painkiller for managing a headache is paracetamol, while non-steroidal anti-inflammatory drugs (NSAIDs) like ibuprofen or aspirin should be avoided in the initial period. While a headache is a common symptom of a concussion, it is essential to manage pain safely to avoid masking more serious symptoms or increasing the risk of complications. This guide outlines the safest medication choices and clear signs that indicate a need for urgent medical attention based on UK health standards. 

What We’ll Discuss in This Article 

The safest painkiller to use for post-concussion headaches. 

Why certain common over-the-counter medications must be avoided. 

The risks associated with anti-inflammatory drugs after a head injury. 

How to safely monitor symptoms while using pain relief. 

When a headache after a head injury becomes a medical emergency. 

Answers to common questions regarding recovery and medication. 

Paracetamol is the primary medication recommended by the NHS for managing pain and headaches following a minor head injury or concussion. It is considered safe because it provides effective pain relief without significantly increasing the risk of bleeding or masking the early signs of more serious intracranial complications. When using paracetamol, it is vital to strictly follow the dosage instructions on the packet or as advised by a healthcare professional. 

Most people find that a post-concussion headache improves with rest and standard doses of paracetamol. It is important not to exceed the maximum dose in a 24-hour period. If the headache does not respond to paracetamol or if the pain is becoming progressively worse, this could indicate a more serious injury and should be assessed by a doctor immediately. For more information on managing mild symptoms, you can visit the NHS guide on head injuries and concussion

Medications to avoid after a head injury 

You should avoid taking non-steroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen or aspirin, for at least the first 48 hours after a concussion unless specifically told otherwise by a doctor. These medications can thin the blood and potentially increase the risk of bleeding on the brain, which is a rare but serious complication of head trauma. Additionally, aspirin should never be given to children under the age of 16 due to the risk of Reye’s syndrome. 

Other medications to avoid include stronger opiate-based painkillers like codeine or dihydrocodeine, as these can cause drowsiness and may make it difficult for medical professionals or carers to assess your level of consciousness or neurological state. Alcohol must also be strictly avoided during the recovery period, as it can worsen symptoms and increase the risk of falls or further injury. Detailed clinical standards on managing these risks are available through the NICE guidelines on head injury assessment

Comparing painkillers for head injuries 

Medication Type Recommended? Reason 
Paracetamol Yes Safest option, does not increase bleeding risk. 
Ibuprofen No (Initial 48hrs) May increase the risk of bleeding after trauma. 
Aspirin No Thins the blood; risk of Reye’s syndrome in children. 
Codeine No Causes drowsiness that can mask serious symptoms. 

When to seek emergency medical help 

While most concussions result in a temporary headache that settles with rest, certain symptoms require an immediate call to 999 or a visit to the nearest A&E department. If a headache is described as the “worst ever” or if it is accompanied by persistent vomiting, it may signal a more severe internal injury. 

Other “red flag” symptoms include: 

Loss of consciousness, even if brief. 

Seizures or fits. 

Weakness in the arms or legs or problems with balance. 

Clear fluid or blood leaking from the ears or nose. 

New deafness in one or both ears. 

Changes in eyesight, such as blurred or double vision. 

Increased confusion, irritability, or unusual behaviour. 

Conclusion 

Managing a concussion requires a cautious approach to pain relief, prioritising paracetamol and avoiding anti-inflammatory drugs like ibuprofen in the early stages. Rest is the most critical component of recovery, allowing the brain time to heal without further strain. Most symptoms will resolve within a few days, but careful monitoring is essential. If you experience severe, sudden, or worsening symptoms, call 999 immediately. 

Can I take ibuprofen if paracetamol doesn’t work? 

You should wait at least 48 hours after the injury before considering ibuprofen, and only if a doctor has confirmed it is safe for you. 

Is it safe to sleep after a concussion? 

Yes, it is safe to sleep, but it is recommended that a responsible adult checks on you regularly during the first 24 hours to ensure you can be easily woken.

How long does a concussion headache usually last?

Most post-concussion headaches improve within a few days, though some people may experience symptoms for two weeks or longer. 

Can I use caffeine for a post-concussion headache?

It is best to avoid caffeine and stimulants during early recovery as they can increase heart rate and potentially worsen headache symptoms. 

When can I return to sports after a head injury?

You should follow a graduated return-to-play protocol as advised by a healthcare professional, usually starting only after you are completely symptom-free without medication. 

Authority Snapshot (E-E-A-T Block) 

This article provides public health information regarding safe medication use following a head injury, authored by our Medical Content Team and reviewed by Dr. Stefan Petrov. The guidance is strictly aligned with NHS and NICE clinical standards to ensure patient safety and accurate self-care advice. It focuses on evidence-based recommendations for minor head trauma management in the UK.

Reviewed by

Dr. Stefan Petrov, MBBS
Dr. Stefan Petrov, MBBS

Dr. Stefan Petrov is a UK-trained physician with an MBBS and postgraduate certifications including Basic Life Support (BLS), Advanced Cardiac Life Support (ACLS), and the UK Medical Licensing Assessment (PLAB 1 & 2). He has hands-on experience in general medicine, surgery, anaesthesia, ophthalmology, and emergency care. Dr. Petrov has worked in both hospital wards and intensive care units, performing diagnostic and therapeutic procedures, and has contributed to medical education by creating patient-focused health content and teaching clinical skills to junior doctors.

All qualifications and professional experience stated above are authentic and verified by our editorial team. However, pseudonym and image likeness are used to protect the reviewer's privacy.