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How Do Dopamine/Norepinephrine Problems Affect ADHD + Anxiety? 

ADHD and anxiety often co-occur, and research suggests that dopamine and norepinephrine dysfunction play a significant role in both conditions. The neurotransmitter imbalance seen in ADHD can also contribute to heightened anxiety symptoms, affecting emotional regulation and making it harder to manage stress, worry, and fear. 

Dopamine and ADHD + Anxiety 

Dopamine is involved in motivation, reward processing, and attention. In ADHD, dopamine dysfunction in areas like the prefrontal cortex can lead to poor focus, impulsivity, and difficulty regulating emotions. When dopamine is underactive, individuals may feel overwhelmed by tasks, leading to anxiety or stress. Moreover, the dopamine-anxiety connection becomes even more complex when the need for immediate rewards or relief becomes a central focus, further amplifying feelings of tension. 

Norepinephrine and Emotional Regulation 

Norepinephrine, which regulates alertness and attention, is also critical for managing the body’s stress response. In individuals with ADHD, norepinephrine dysfunction can cause heightened anxiety, as it affects the brain’s ability to filter out distractions and maintain focus under pressure. When norepinephrine levels are unbalanced, it can contribute to emotional dysregulation, making it difficult to manage anxiety, even in everyday situations. The overlapping symptoms of impulsivity, restlessness, and hyperactivity in ADHD often worsen anxiety when norepinephrine is not functioning optimally. 

Comorbidity and Treatment 

When ADHD and anxiety co-occur, treating both conditions requires addressing dopamine and norepinephrine imbalances. Medications such as SSRIs (for anxiety) and stimulants or non-stimulants (for ADHD) may help regulate these neurotransmitters. However, therapy and lifestyle changes, such as cognitive-behavioral therapy (CBT), are also crucial to improving emotional regulation and managing anxiety symptoms alongside ADHD. 

Visit providers like ADHD Certify for personal consultations to explore how dopamine and norepinephrine imbalances contribute to ADHD and anxiety.

For a deeper dive into the science, diagnosis, and full treatment landscape, read our complete guide to Dopamine and norepinephrine systems.

Victoria Rowe, MSc, author for my patient advice - mypatientadvice.co.uk

Victoria Rowe, MSc

Author

Victoria Rowe is a health psychologist with a Master’s in Health Psychology and a BS in Applied Psychology. She has experience as a school psychologist, conducting behavioural assessments, developing individualized education plans (IEPs), and supporting children’s mental health. Dr. Rowe has contributed to peer-reviewed research on mental health, including studies on anxiety disorders and the impact of COVID-19 on healthcare systems. Skilled in SPSS, Minitab, and academic writing, she is committed to advancing psychological knowledge and promoting well-being through evidence-based practice.

All qualifications and professional experience stated above are authentic and verified by our editorial team. However, pseudonym and image likeness are used to protect the author's privacy. 

Dr. Rebecca Fernandez, MBBS, author and a reviewer for my patient advice - mypatientadvice.co.uk

Dr. Rebecca Fernandez, MBBS

Reviewer

Dr. Rebecca Fernandez is a UK-trained physician with an MBBS and experience in general surgery, cardiology, internal medicine, gynecology, intensive care, and emergency medicine. She has managed critically ill patients, stabilised acute trauma cases, and provided comprehensive inpatient and outpatient care. In psychiatry, Dr. Fernandez has worked with psychotic, mood, anxiety, and substance use disorders, applying evidence-based approaches such as CBT, ACT, and mindfulness-based therapies. Her skills span patient assessment, treatment planning, and the integration of digital health solutions to support mental well-being.

All qualifications and professional experience stated above are authentic and verified by our editorial team. However, pseudonym and image likeness are used to protect the reviewer's privacy.