What Does the ENIGMA Imaging Project Reveal About ADHD? 

The ENIGMA ADHD imaging project is a landmark initiative that provides valuable insights into the brain differences associated with ADHD. By pooling data from large-scale studies across the globe, the project offers a clearer understanding of how ADHD affects brain structure and function, using cutting-edge neuroimaging techniques. 

Key Findings from the ENIGMA ADHD Imaging Project 

One of the key revelations from the ENIGMA ADHD project is the brain volume differences seen in individuals with ADHD. The research found that people with ADHD often have smaller brain volumes, particularly in regions like the prefrontal cortex and basal ganglia, which play critical roles in attention, decision-making, and impulse control. These findings have helped highlight the biological underpinnings of ADHD, offering a clearer distinction from other neurodevelopmental disorders. 

The ENIGMA ADHD imaging project also emphasizes the importance of international collaboration, bringing together data from diverse populations to create a comprehensive global picture of ADHD. This collaborative effort allows for more robust, generalizable findings that improve our understanding of ADHD’s impact across different cultural and demographic groups. 

How It Helps with Diagnosis and Treatment 

Understanding these brain volume differences can be pivotal for better diagnosis and treatment. By identifying which areas of the brain are affected, clinicians can tailor treatment plans, potentially improving the effectiveness of interventions such as medication and CBT. The project also helps guide future research into ADHD, leading to more accurate biomarkers for the disorder. 

Visit providers like ADHD Certify for personal consultations tailored to your ADHD care and support needs. 

For a deeper dive into the science, diagnosis, and full treatment landscape, read our complete guide to ENIGMA ADHD imaging.

Phoebe Carter, MSc

Author

Phoebe Carter is a clinical psychologist with a Master’s in Clinical Psychology and a Bachelor’s in Applied Psychology. She has experience working with both children and adults, conducting psychological assessments, developing individualized treatment plans, and delivering evidence-based therapies. Phoebe specialises in neurodevelopmental conditions such as autism spectrum disorder (ASD), ADHD, and learning disabilities, as well as mood, anxiety, psychotic, and personality disorders. She is skilled in CBT, behaviour modification, ABA, and motivational interviewing, and is dedicated to providing compassionate, evidence-based mental health care to individuals of all ages.

All qualifications and professional experience stated above are authentic and verified by our editorial team. However, pseudonym and image likeness are used to protect the author's privacy. 

Dr. Rebecca Fernandez, MBBS

Reviewer

Dr. Rebecca Fernandez is a UK-trained physician with an MBBS and experience in general surgery, cardiology, internal medicine, gynecology, intensive care, and emergency medicine. She has managed critically ill patients, stabilised acute trauma cases, and provided comprehensive inpatient and outpatient care. In psychiatry, Dr. Fernandez has worked with psychotic, mood, anxiety, and substance use disorders, applying evidence-based approaches such as CBT, ACT, and mindfulness-based therapies. Her skills span patient assessment, treatment planning, and the integration of digital health solutions to support mental well-being.

All qualifications and professional experience stated above are authentic and verified by our editorial team. However, pseudonym and image likeness are used to protect the reviewer's privacy.