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Can genetic factors explain the co-occurrence of ADHD and conduct disorder? 

PostedAugust 19, 2025
UpdatedSeptember 4, 2025
ByMy Patient Advice

Absolutely. Studies in ADHD and conduct disorder genetics show that these two conditions often arise from overlapping inherited vulnerabilities. While ADHD centers on impulsivity and attention, conduct disorder involves behavioural defiance or rule-breaking, yet many individuals experience both, suggesting a shared biological backdrop. 

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How shared genetics influence both conditions 

Here’s what researchers and clinicians have discovered about their genetic intersection. 

Behavioural genetics perspective 

Twin and family studies highlight a common genetic component underlying impulsive behaviours, emotional dysregulation, and aggression. This behavioural genetics link helps explain why ADHD and conduct disorder tend to appear together more often than by chance. 

Antisocial traits and impulsivity

 Gene variants related to dopamine and serotonin function can elevate the risk for impulsive, aggressive, or risk-taking behaviours, characteristics common in both ADHD and conduct issues. These antisocial traits often reflect similar underlying neurobiological pathways. 

Shared etiology model 

Rather than viewing each condition in isolation, the shared etiology model recognises that some genetic factors cut across diagnostic boundaries, making it more likely for both ADHD and conduct disorder to appear within the same individual or family. 

Emerging insights into ADHD and conduct disorder genetics support a unified approach to diagnosis and treatment. Visit providers like ADHD Certify for evaluations that consider overlapping traits and integrated treatment planning. 

For a deeper dive into the science, diagnosis, and full treatment landscape, read our complete guide to Genetic Factors in ADHD. 

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Lucia Alvarez, MSc, author for my patient advice - mypatientadvice.co.uk

Lucia Alvarez, MSc

Author

Lucia Alvarez is a clinical psychologist with a Master’s in Clinical Psychology and extensive experience providing evidence-based therapy and psychological assessment to children, adolescents, and adults. Skilled in CBT, DBT, and other therapeutic interventions, she has worked in hospital, community, and residential care settings. Her expertise includes grief counseling, anxiety management, and resilience-building, with a strong focus on creating safe, supportive environments to improve mental well-being.

All qualifications and professional experience stated above are authentic and verified by our editorial team. However, pseudonym and image likeness are used to protect the author's privacy. 

Dr. Rebecca Fernandez, MBBS, author and a reviewer for my patient advice - mypatientadvice.co.uk

Dr. Rebecca Fernandez, MBBS

Reviewer

Dr. Rebecca Fernandez is a UK-trained physician with an MBBS and experience in general surgery, cardiology, internal medicine, gynecology, intensive care, and emergency medicine. She has managed critically ill patients, stabilised acute trauma cases, and provided comprehensive inpatient and outpatient care. In psychiatry, Dr. Fernandez has worked with psychotic, mood, anxiety, and substance use disorders, applying evidence-based approaches such as CBT, ACT, and mindfulness-based therapies. Her skills span patient assessment, treatment planning, and the integration of digital health solutions to support mental well-being.

All qualifications and professional experience stated above are authentic and verified by our editorial team. However, pseudonym and image likeness are used to protect the reviewer's privacy. 

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