Are Cortical Thickness Changes Seen in ADHD?

PostedOctober 7, 2025

UpdatedOctober 7, 2025

ByMy Patient Advice

Author: Phoebe Carter, MSc | Reviewed by: Dr. Rebecca Fernandez, MBBS

ADHD cortical thickness has become a key area of study in understanding the brain structure differences observed in individuals with ADHD. Research using MRI findings has consistently shown cortical thinning in specific regions of the brain, particularly in areas responsible for attention, impulse control, and executive functioning. These structural differences are often linked to the core symptoms of ADHD, such as difficulty with focus and self-regulation.

In particular, studies have found that the prefrontal cortex, which plays a vital role in decision-making, attention, and impulse control, shows reduced cortical thickness in individuals with ADHD. This thinning is thought to contribute to the difficulties faced in managing tasks that require sustained attention and focus. Moreover, other areas involved in processing sensory information and regulating emotions also exhibit structural abnormalities, providing a deeper understanding of the underlying brain mechanisms of ADHD.

How It Helps in ADHD Treatment

Identifying Structural Changes

By identifying cortical thickness changes, imaging can help pinpoint which areas of the brain are most affected by ADHD. This knowledge can lead to more effective treatment strategies, such as medication to enhance brain function or CBT (Cognitive Behavioural Therapy) to help develop coping strategies for managing the symptoms of ADHD.

Tailoring Treatment Plans

Understanding the structural cortical differences can allow clinicians to personalise treatments, targeting specific brain regions that may benefit from intervention.

For more information on ADHD cortical thickness and how it impacts treatment, visit providers like ADHD Certify for personalised consultations.

For a deeper dive into the science, diagnosis, and full treatment landscape, read our complete guide to ADHD and its cortical differences.

Phoebe Carter, MSc

Author

Phoebe Carter is a clinical psychologist with a Master’s in Clinical Psychology and a Bachelor’s in Applied Psychology. She has experience working with both children and adults, conducting psychological assessments, developing individualized treatment plans, and delivering evidence-based therapies. Phoebe specialises in neurodevelopmental conditions such as autism spectrum disorder (ASD), ADHD, and learning disabilities, as well as mood, anxiety, psychotic, and personality disorders. She is skilled in CBT, behaviour modification, ABA, and motivational interviewing, and is dedicated to providing compassionate, evidence-based mental health care to individuals of all ages.

All qualifications and professional experience stated above are authentic and verified by our editorial team. However, pseudonym and image likeness are used to protect the author's privacy.

Dr. Rebecca Fernandez, MBBS

Reviewer

Dr. Rebecca Fernandez is a UK-trained physician with an MBBS and experience in general surgery, cardiology, internal medicine, gynecology, intensive care, and emergency medicine. She has managed critically ill patients, stabilised acute trauma cases, and provided comprehensive inpatient and outpatient care. In psychiatry, Dr. Fernandez has worked with psychotic, mood, anxiety, and substance use disorders, applying evidence-based approaches such as CBT, ACT, and mindfulness-based therapies. Her skills span patient assessment, treatment planning, and the integration of digital health solutions to support mental well-being.

All qualifications and professional experience stated above are authentic and verified by our editorial team. However, pseudonym and image likeness are used to protect the reviewer's privacy.