Are There Structural Asymmetries in ADHD Brain Scans?

PostedOctober 6, 2025

UpdatedOctober 6, 2025

ByMy Patient Advice

Author: Phoebe Carter, MSc | Reviewed by: Dr. Rebecca Fernandez, MBBS

Yes, ADHD brain asymmetry has been consistently observed in neuroimaging studies, revealing that people with ADHD often show hemispheric differences in both structure and function. Using advanced MRI studies, researchers have found that the left and right sides of the brain can develop unevenly, particularly in regions responsible for attention, motor control, and emotional regulation. These lateralisation patterns may influence how symptoms appear and vary from person to person.

For instance, structural asymmetries have been noted in the prefrontal cortex, parietal lobes, and caudate nucleus, all of which are involved in executive function, inhibition, and focus. Children with more pronounced brain asymmetry often exhibit stronger ADHD traits, suggesting these physical differences could be a marker of symptom severity. While not used diagnostically, these findings help explain some of the neurobiological complexity behind ADHD.

Symptoms Influenced by Brain Asymmetry in ADHD

Below are examples of how brain lateralisation may impact common ADHD symptoms, with treatments that may help address them:

Uneven Attention or Spatial Bias

Some individuals with ADHD may struggle with focusing evenly across their visual field or show delayed reactions on one side, likely linked to parietal lobe asymmetry. Stimulant medications can improve attention across both hemispheres, while CBT can help individuals develop strategies to balance awareness and response.

Inhibitory Control Issues

Asymmetries in the prefrontal cortex or caudate may lead to difficulties stopping impulses or switching tasks. Medication can help regulate these neural pathways, while behavioural therapies support better control and decision-making.

Visit providers like ADHD Certify for personal consultations tailored to your ADHD care and support.

For a deeper dive into the science, diagnosis, and full treatment landscape, read our complete guide to ADHD brain asymmetry.

Phoebe Carter, MSc

Author

Phoebe Carter is a clinical psychologist with a Master’s in Clinical Psychology and a Bachelor’s in Applied Psychology. She has experience working with both children and adults, conducting psychological assessments, developing individualized treatment plans, and delivering evidence-based therapies. Phoebe specialises in neurodevelopmental conditions such as autism spectrum disorder (ASD), ADHD, and learning disabilities, as well as mood, anxiety, psychotic, and personality disorders. She is skilled in CBT, behaviour modification, ABA, and motivational interviewing, and is dedicated to providing compassionate, evidence-based mental health care to individuals of all ages.

All qualifications and professional experience stated above are authentic and verified by our editorial team. However, pseudonym and image likeness are used to protect the author's privacy.

Dr. Rebecca Fernandez, MBBS

Reviewer

Dr. Rebecca Fernandez is a UK-trained physician with an MBBS and experience in general surgery, cardiology, internal medicine, gynecology, intensive care, and emergency medicine. She has managed critically ill patients, stabilised acute trauma cases, and provided comprehensive inpatient and outpatient care. In psychiatry, Dr. Fernandez has worked with psychotic, mood, anxiety, and substance use disorders, applying evidence-based approaches such as CBT, ACT, and mindfulness-based therapies. Her skills span patient assessment, treatment planning, and the integration of digital health solutions to support mental well-being.

All qualifications and professional experience stated above are authentic and verified by our editorial team. However, pseudonym and image likeness are used to protect the reviewer's privacy.