What Does ADHD Look Like on SPECT Scans?

PostedOctober 6, 2025

UpdatedOctober 6, 2025

ByMy Patient Advice

Author: Phoebe Carter, MSc | Reviewed by: Dr. Rebecca Fernandez, MBBS

ADHD SPECT imaging reveals distinctive patterns of cerebral blood flow using nuclear imaging technology and regional brain activity patterns. On SPECT (Single Photon Emission Computed Tomography) scans, people with ADHD often show underactivity in areas like the prefrontal cortex and striatum, and sometimes overactivity in sensory or motor regions. These patterns may help explain symptoms such as impulsivity, poor attention, and emotional dysregulation.

In SPECT scans of ADHD brains, several studies have found reduced perfusion (less blood flow) in parts of the brain involved in executive functions. For example, one of the early studies reported lower perfusion in the right striatum among children with ADHD. Some scans also show that after administering stimulant medications, blood flow in certain regions improves, suggesting these imaging patterns are dynamic and responsive to treatment. However, it’s important to note that SPECT is not currently considered a diagnostic tool in mainstream practice; it’s more of a supplementary window into how ADHD may manifest in brain blood flow.

How SPECT Findings Connect to ADHD Symptoms

Below are key symptoms often associated with SPECT imaging patterns, and how treatment may help:

Inattention and Poor Focus

Reduced blood flow in the prefrontal cortex can correlate with difficulties concentrating, organising tasks, and resisting distraction. Stimulant medication may increase perfusion and improve attention, while CBT offers skills to structure daily life and enhance focus.

Impulsivity and Restlessness

Changes in the striatum or other executive control areas may lead to impulsive actions or trouble sitting still. Medication can help regulate activity in those regions, while behaviour-based therapies can teach strategies to manage urges and improve self-control.

Visit providers like ADHD Certify for personal consultations tailored to your ADHD care and support.

For a deeper dive into the science, diagnosis, and full treatment landscape, read our complete guide to ADHD SPECT imaging.

Phoebe Carter, MSc

Author

Phoebe Carter is a clinical psychologist with a Master’s in Clinical Psychology and a Bachelor’s in Applied Psychology. She has experience working with both children and adults, conducting psychological assessments, developing individualized treatment plans, and delivering evidence-based therapies. Phoebe specialises in neurodevelopmental conditions such as autism spectrum disorder (ASD), ADHD, and learning disabilities, as well as mood, anxiety, psychotic, and personality disorders. She is skilled in CBT, behaviour modification, ABA, and motivational interviewing, and is dedicated to providing compassionate, evidence-based mental health care to individuals of all ages.

All qualifications and professional experience stated above are authentic and verified by our editorial team. However, pseudonym and image likeness are used to protect the author's privacy.

Dr. Rebecca Fernandez, MBBS

Reviewer

Dr. Rebecca Fernandez is a UK-trained physician with an MBBS and experience in general surgery, cardiology, internal medicine, gynecology, intensive care, and emergency medicine. She has managed critically ill patients, stabilised acute trauma cases, and provided comprehensive inpatient and outpatient care. In psychiatry, Dr. Fernandez has worked with psychotic, mood, anxiety, and substance use disorders, applying evidence-based approaches such as CBT, ACT, and mindfulness-based therapies. Her skills span patient assessment, treatment planning, and the integration of digital health solutions to support mental well-being.

All qualifications and professional experience stated above are authentic and verified by our editorial team. However, pseudonym and image likeness are used to protect the reviewer's privacy.