Which Supplements Raise Dopamine and Norepinephrine in ADHD?

PostedSeptember 30, 2025

UpdatedSeptember 30, 2025

ByMy Patient Advice

Author: Victoria Rowe, MSc | Reviewed by: Dr. Rebecca Fernandez, MBBS

Managing ADHD often involves a multi-faceted approach, including medication, therapy, and lifestyle changes. One promising complementary strategy is the use of supplements to help raise dopamine and norepinephrine levels, which are often dysregulated in ADHD. Certain vitamins and nutraceuticals can support these neurotransmitter systems, potentially improving focus, motivation, and emotional regulation naturally.

Supplements That Support Dopamine and Norepinephrine

Supplements like omega-3s, L-tyrosine, magnesium, and B-vitamins may support dopamine and norepinephrine balance, aiding focus, mood, and cognitive function.

L-Tyrosine

This amino acid is a precursor to both dopamine and norepinephrine. Supplementing with L-Tyrosine may help increase the production of these neurotransmitters, supporting cognitive function, attention, and emotional balance. It has been shown to improve stress resilience and mental performance, particularly during demanding tasks.

Omega-3 Fatty Acids

Found in fish oil or flaxseed oil, omega-3 fatty acids are essential for brain health and have been shown to help regulate dopamine and norepinephrine function. They support the structure and function of brain cells, improving mood, attention, and cognitive flexibility, which are often impaired in ADHD.

Vitamin D

Vitamin D has a crucial role in the production of dopamine. Low levels of vitamin D have been associated with ADHD symptoms, and supplementing with vitamin D can potentially help restore balance in dopamine levels, improving attention and focus.

B-Vitamins

Particularly, B6 and B12, these vitamins support the synthesis of dopamine and norepinephrine. B6 helps in the conversion of L-tyrosine to dopamine, while B12 supports overall brain function and energy, helping reduce ADHD symptoms like fatigue and irritability.

Rhodiola Rosea

An adaptogen, Rhodiola Rosea, has been found to support norepinephrine and dopamine levels, enhancing focus and reducing fatigue, especially under stress.

Conclusion

While supplements can help support dopamine and norepinephrine balance, they should be considered as part of a broader ADHD management plan. Always consult with a healthcare provider before starting new supplements, as individual needs vary.

Visit providers like ADHD Certify for personal consultations to explore supplements that support dopamine and norepinephrine in managing ADHD.

For a deeper dive into the science, diagnosis, and full treatment landscape, read our complete guide to Dopamine and norepinephrine systems.

Victoria Rowe, MSc

Author

Victoria Rowe is a health psychologist with a Master’s in Health Psychology and a BS in Applied Psychology. She has experience as a school psychologist, conducting behavioural assessments, developing individualized education plans (IEPs), and supporting children’s mental health. Dr. Rowe has contributed to peer-reviewed research on mental health, including studies on anxiety disorders and the impact of COVID-19 on healthcare systems. Skilled in SPSS, Minitab, and academic writing, she is committed to advancing psychological knowledge and promoting well-being through evidence-based practice.

All qualifications and professional experience stated above are authentic and verified by our editorial team. However, pseudonym and image likeness are used to protect the author's privacy.

Dr. Rebecca Fernandez, MBBS

Reviewer

Dr. Rebecca Fernandez is a UK-trained physician with an MBBS and experience in general surgery, cardiology, internal medicine, gynecology, intensive care, and emergency medicine. She has managed critically ill patients, stabilised acute trauma cases, and provided comprehensive inpatient and outpatient care. In psychiatry, Dr. Fernandez has worked with psychotic, mood, anxiety, and substance use disorders, applying evidence-based approaches such as CBT, ACT, and mindfulness-based therapies. Her skills span patient assessment, treatment planning, and the integration of digital health solutions to support mental well-being.

All qualifications and professional experience stated above are authentic and verified by our editorial team. However, pseudonym and image likeness are used to protect the reviewer's privacy.