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Autism MOB

What Types of Infections During Pregnancy Are Linked to Autism Risk? 

Posted:    Author:  

Hannah Smith, MSc

   Reviewed by:  

Dr. Rebecca Fernandez, MBBS

Researchers have increasingly studied the link between infections during pregnancy and autism, uncovering evidence that certain illnesses experienced during pregnancy may influence a child’s risk of developing autism. In particular, infections during pregnancy and autism risk are often connected through the body’s immune response, which can interfere with foetal brain development during key stages. 

Different types of infections can pose varying levels of risk. Both viral infections and bacterial infections have been examined for their potential role in disrupting neural development. When a pregnant person’s immune system is activated, inflammatory molecules can cross the placenta, potentially affecting how the brain forms and functions. This is one of the leading theories connecting infections during pregnancy and autism risk. 

Common Infections During Pregnancy and Autism Risk Factors 

Here are some specific examples of infections during pregnancy and autism risk, and how they may impact development: 

Viral infections 

Viral infections such as influenza, rubella, or cytomegalovirus (CMV) have been linked to increased autism risk, especially when contracted during the second trimester. These infections can trigger a strong immune response, leading to inflammation that may interfere with foetal brain growth. 

Bacterial infections 

Bacterial infections, including urinary tract infections (UTIs) and certain gastrointestinal infections, have also been associated with a higher chance of pregnancy complications. These complications may indirectly affect neurodevelopment and contribute to autism risk. 

Severity and timing of infection 

The severity and timing of infections during pregnancy and autism outcomes are closely related. Infections occurring during the first or second trimester tend to pose greater risk, particularly when they lead to prolonged fever or untreated inflammation. 

Visit providers like Autism Detect for personal consultations to understand how infections during pregnancy and autism risk may apply to your pregnancy and explore preventative health strategies. 

For a deeper dive into the science, diagnosis, and full treatment landscape, read our complete guide to Maternal Health and Infections. 

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Autism MOB
Hannah Smith, MSc
Written By Hannah Smith, MSc

Hannah Smith is a clinical psychologist with a Master’s in Clinical Psychology and over three years of experience in behaviour therapy, special education, and inclusive practices. She specialises in Applied Behavior Analysis (ABA), Cognitive Behavioural Therapy (CBT), and inclusive education strategies. Hannah has worked extensively with children and adults with Autism Spectrum Disorder (ASD), ADHD, Down syndrome, and intellectual disabilities, delivering evidence-based interventions to support development, mental health, and well-being.

All qualifications and professional experience stated above are authentic and verified by our editorial team. However, pseudonym and image likeness are used to protect the author's privacy. 
Dr. Rebecca Fernandez, MBBS
Reviewed By Dr. Rebecca Fernandez, MBBS

Dr. Rebecca Fernandez is a UK-trained physician with an MBBS and experience in general surgery, cardiology, internal medicine, gynecology, intensive care, and emergency medicine. She has managed critically ill patients, stabilised acute trauma cases, and provided comprehensive inpatient and outpatient care. In psychiatry, Dr. Fernandez has worked with psychotic, mood, anxiety, and substance use disorders, applying evidence-based approaches such as CBT, ACT, and mindfulness-based therapies. Her skills span patient assessment, treatment planning, and the integration of digital health solutions to support mental well-being.

All qualifications and professional experience stated above are authentic and verified by our editorial team. However, pseudonym and image likeness are used to protect the reviewer's privacy. 

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