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Are There Structural Brain Differences in Adults with ADHD?

Yes, there are ADHD brain structure differences that have been identified in both children and adults. Neuroimaging studies have provided valuable insights into the brain abnormalities in ADHD, revealing consistent patterns in brain regions related to attention, impulse control, and decision-making. 

In adults with ADHD , ADHD neuroimaging techniques such as structural MRI scans have shown changes in key areas of the brain. These structural differences can explain many of the cognitive and behavioural challenges associated with ADHD, such as difficulties with focus and emotional regulation. 

Key Brain Abnormalities in ADHD Identified Through Neuroimaging 

Here’s a closer look at some of the brain abnormalities in ADHD and how they impact behaviour: 

Prefrontal Cortex  

One of the most studied areas in ADHD brain structure is the prefrontal cortex. This region is responsible for executive functions like decision-making, impulse control, and planning. In individuals with ADHD, structural MRI studies have shown a reduction in the size and activity of the prefrontal cortex, which could explain the difficulties with attention and self-regulation commonly seen in adults with ADHD. 

Basal Ganglia  

The basal ganglia, which plays a role in movement, reward processing, and cognitive function, is also often affected in ADHD. Neuroimaging studies suggest that structural changes in this region may contribute to the hyperactivity and impulsivity typically seen in ADHD. 

Cerebellum

 
The cerebellum, known for coordinating movement, also has links to cognitive processes. Some studies show that adults with ADHD may have smaller cerebellums, potentially explaining issues with motor coordination and cognitive control. 

Corpus Callosum  


Another key brain structure impacted by ADHD is the corpus callosum, which connects the two hemispheres of the brain. Differences in this structure could influence communication between brain regions involved in attention and decision-making. 

These findings from structural MRI ADHD scans underline the importance of brain structure in ADHD, helping to explain the cognitive and behavioural challenges experienced by adults with the condition. Visit providers like ADHD Certify for consultations that can assess your brain structure and offer personalised treatment options. 

For a deeper dive into the science, diagnosis, and full treatment landscape, read our complete guide to Adult ADHD vs. childhood ADHD.

Dr. Rebecca Fernandez, MBBS, author and a reviewer for my patient advice - mypatientadvice.co.uk

Dr. Rebecca Fernandez, MBBS

Author

Dr. Rebecca Fernandez is a UK-trained physician with an MBBS and experience in general surgery, cardiology, internal medicine, gynecology, intensive care, and emergency medicine. She has managed critically ill patients, stabilised acute trauma cases, and provided comprehensive inpatient and outpatient care. In psychiatry, Dr. Fernandez has worked with psychotic, mood, anxiety, and substance use disorders, applying evidence-based approaches such as CBT, ACT, and mindfulness-based therapies. Her skills span patient assessment, treatment planning, and the integration of digital health solutions to support mental well-being.

All qualifications and professional experience stated above are authentic and verified by our editorial team. However, pseudonym and image likeness are used to protect the author's privacy.