Are Hippocampal Differences Seen in ADHD Brain Scans? 

Yes, research increasingly shows that the ADHD hippocampus may display structural and functional differences when compared to neurotypical brains. These MRI differences include reduced volume or altered shape in the hippocampus, a region key to memory functions, learning, and emotional regulation. While not yet used as diagnostic criteria, these structural abnormalities provide further biological context for ADHD symptoms. 

The hippocampus helps encode and organise short- and long-term memories, while also playing a role in navigating stress. In individuals with ADHD, changes in this region have been linked to issues with working memory, information recall, and emotional reactivity. These insights support the idea that ADHD impacts more than just attention and hyperactivity, it involves wider brain networks tied to learning and emotional balance. 

Key Symptoms Linked to Hippocampal Differences 

Below are common ADHD-related symptoms associated with hippocampal changes, along with treatment strategies that may help. 

Working Memory and Learning Struggles 

Reduced hippocampal volume may contribute to difficulty remembering instructions, staying organised, or learning new information. CBT can teach memory reinforcement techniques, while medication may improve focus during tasks that require memory engagement. 

Heightened Emotional Sensitivity 

Because the hippocampus interacts with areas responsible for emotional regulation, differences here may lead to overreactions or stress overload. Behavioural therapy can help build resilience and coping strategies, while medication may support overall mood stability. 

Visit providers like ADHD Certify for personal consultations tailored to your ADHD care and support. 

For a deeper dive into the science, diagnosis, and full treatment landscape, read our complete guide to ADHD hippocampus.