my patient advice logo - used for header - mypatientadvice.co.uk
All Topics
Contact Us
Free Health Updates
Table of Contents
< All Topics
Print

How is ADHD Linked to Genetic Brain Structure Markers? 

PostedOctober 7, 2025
UpdatedOctober 7, 2025
ByMy Patient Advice

Research into ADHD brain markers has revealed significant connections between genetic factors and brain structure, offering a deeper understanding of how ADHD develops. Advances in neurobiology and neuroimaging have highlighted structural differences in specific brain regions, such as the prefrontal cortex and basal ganglia, that may be linked to the genetic basis of ADHD. 

Get your Private ADHD assessment

Exploring the Genetic Brain Structure Link 

Studies have shown that genetic brain markers can be identified using techniques like MRI and DTI imaging, revealing structural differences and abnormalities in areas responsible for attention, impulsivity, and executive functioning. These differences, particularly in the prefrontal cortex, align with findings in individuals with ADHD, suggesting that certain inherited genetic variations may affect brain development. The emerging field of imaging-genetics aims to connect these brain structure markers with specific genes, offering new insights into the neurobiological mechanisms behind ADHD. 

How This Knowledge Helps 

Understanding the link between genetic brain markers and ADHD can guide more personalised treatment approaches. For example, medication targeting the dopamine system or CBT for improving executive function can be tailored to the individual’s genetic and brain structure profile, potentially enhancing treatment outcomes. 

Visit providers like ADHD Certify for personal consultations tailored to your ADHD care and support needs. 

For a deeper dive into the science, diagnosis, and full treatment landscape, read our complete guide to ADHD fMRI tasks.

Get your Private ADHD assessment

Phoebe Carter, MSc

Author

Phoebe Carter is a clinical psychologist with a Master’s in Clinical Psychology and a Bachelor’s in Applied Psychology. She has experience working with both children and adults, conducting psychological assessments, developing individualized treatment plans, and delivering evidence-based therapies. Phoebe specialises in neurodevelopmental conditions such as autism spectrum disorder (ASD), ADHD, and learning disabilities, as well as mood, anxiety, psychotic, and personality disorders. She is skilled in CBT, behaviour modification, ABA, and motivational interviewing, and is dedicated to providing compassionate, evidence-based mental health care to individuals of all ages.

All qualifications and professional experience stated above are authentic and verified by our editorial team. However, pseudonym and image likeness are used to protect the author's privacy. 

Dr. Rebecca Fernandez, MBBS, author and a reviewer for my patient advice - mypatientadvice.co.uk

Dr. Rebecca Fernandez, MBBS

Reviewer

Dr. Rebecca Fernandez is a UK-trained physician with an MBBS and experience in general surgery, cardiology, internal medicine, gynecology, intensive care, and emergency medicine. She has managed critically ill patients, stabilised acute trauma cases, and provided comprehensive inpatient and outpatient care. In psychiatry, Dr. Fernandez has worked with psychotic, mood, anxiety, and substance use disorders, applying evidence-based approaches such as CBT, ACT, and mindfulness-based therapies. Her skills span patient assessment, treatment planning, and the integration of digital health solutions to support mental well-being.

All qualifications and professional experience stated above are authentic and verified by our editorial team. However, pseudonym and image likeness are used to protect the reviewer's privacy. 

Let’s get started on something great

Sign Up for our FREE monthly medical updates. No spamming! Only the best content summary from the month on all medical topics

© 2025 My Patient Advice. All rights reserved.