What Alterations in the Salience Network Appear in ADHD? 

In people with ADHD salience network studies, neuroimaging shows notable connectivity changes in the brain circuits responsible for identifying and prioritising important stimuli. These changes often affect regions like the anterior insula and dorsal anterior cingulate cortex and impact how well someone with ADHD can shift their attention from internal thoughts or distractions to the task at hand. Attention shifting therefore becomes less efficient, leading to some of the characteristic struggles seen in ADHD. 

Research reveals that in ADHD, the salience network shows hyper‑connectivity within itself but weaker ties to other networks such as the default mode network (DMN) and executive control networks. This imbalance in brain circuits means that the salience network may overreact to irrelevant stimuli (internal or external), causing lapses in focus and increased distractibility. Imaging studies also show that the network’s ability to switch between resting‑state and task‑focused states is reduced, further contributing to attentional difficulties.  

Common Symptoms Linked to Salience Network Alterations 

Below are symptoms tied to these network issues, and ways treatment may help: 

Difficulty With Task Switching & Distraction 

Someone may feel pulled away by thoughts or background noises, unable to shift focus to what matters. Medication (especially stimulants) can help stabilise network activity and improve connectivity changes, while CBT can offer techniques that train attention shifting and response control. 

Increased Emotional Reactivity & Impulse Control Problems 

Overactive internal signalling in salience circuits may result in emotional outbursts or impulsive actions when something seems immediately important. Behavioural therapy helps with regulating responses, and medication supports more balanced functioning of the affected brain circuits. 

Visit providers like ADHD Certify for personal consultations tailored to your ADHD care and support needs. 

For a deeper dive into the science, diagnosis, and full treatment landscape, read our complete guide to ADHD salience network.