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Can Neuroimaging Be Used as a Biomarker in ADHD? 

The use of neuroimaging biomarkers in ADHD research has opened exciting possibilities for understanding the brain’s structure and function in affected individuals. Tools like MRI, fMRI, and DTI are being explored not just for scientific insight, but also for their potential as biomarkers to aid in diagnosis, monitoring, and personalised treatment planning. 

What Brain Scans Show in ADHD 

Studies using structural MRI have consistently shown differences in brain regions tied to attention, impulse control, and executive function, particularly the prefrontal cortex, basal ganglia, and cerebellum. Children with ADHD often have smaller total brain volumes and delayed cortical maturation compared to neurotypical peers. 

Functional MRI (fMRI) provides additional insight by tracking real-time brain activity. People with ADHD often show reduced activity in the default mode network (DMN) and altered connectivity in networks that govern attention and inhibition. Meanwhile, diffusion tensor imaging (DTI) reveals microstructural differences in white matter tracts, suggesting altered neural communication pathways. 

Can These Scans Be Used Clinically? 

Although these findings are robust at the group level, neuroimaging biomarkers are not yet reliable enough for routine clinical diagnosis. Variability between individuals and the high cost of brain scans make them impractical for everyday use for now. However, ongoing research aims to refine these methods into tools that could complement behavioural assessments in complex cases. 

Conclusion 

Neuroimaging biomarkers offer a promising window into the ADHD brain and may one day enhance diagnosis and treatment. Visit providers like ADHD Certify for personal consultations and information on cutting-edge neuroimaging tools in ADHD care.

For a deeper dive into the science, diagnosis, and full treatment landscape, read our complete guide to Genetic studies and biomarkers.

Victoria Rowe, MSc, author for my patient advice - mypatientadvice.co.uk

Victoria Rowe, MSc

Author

Victoria Rowe is a health psychologist with a Master’s in Health Psychology and a BS in Applied Psychology. She has experience as a school psychologist, conducting behavioural assessments, developing individualized education plans (IEPs), and supporting children’s mental health. Dr. Rowe has contributed to peer-reviewed research on mental health, including studies on anxiety disorders and the impact of COVID-19 on healthcare systems. Skilled in SPSS, Minitab, and academic writing, she is committed to advancing psychological knowledge and promoting well-being through evidence-based practice.

All qualifications and professional experience stated above are authentic and verified by our editorial team. However, pseudonym and image likeness are used to protect the author's privacy. 

Dr. Rebecca Fernandez, MBBS, author and a reviewer for my patient advice - mypatientadvice.co.uk

Dr. Rebecca Fernandez, MBBS

Reviewer

Dr. Rebecca Fernandez is a UK-trained physician with an MBBS and experience in general surgery, cardiology, internal medicine, gynecology, intensive care, and emergency medicine. She has managed critically ill patients, stabilised acute trauma cases, and provided comprehensive inpatient and outpatient care. In psychiatry, Dr. Fernandez has worked with psychotic, mood, anxiety, and substance use disorders, applying evidence-based approaches such as CBT, ACT, and mindfulness-based therapies. Her skills span patient assessment, treatment planning, and the integration of digital health solutions to support mental well-being.

All qualifications and professional experience stated above are authentic and verified by our editorial team. However, pseudonym and image likeness are used to protect the reviewer's privacy.