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What Percentage of ADHD Patients Experience Major Depressive Disorder? 

PostedSeptember 8, 2025
UpdatedSeptember 8, 2025
ByMy Patient Advice

A significant percentage of individuals with ADHD also experience major depressive disorder in ADHD. Studies show that approximately 30% to 50% of people with ADHD will experience major depressive disorder at some point in their lives. The major depressive disorder in ADHD is a common comorbidity, and its impact can be severe, complicating the management of ADHD symptoms. 

The diagnosis rates for major depressive disorder in ADHD are high, as both conditions share similar symptoms such as irritability, emotional instability, and difficulty with concentration. The presence of depression can often make ADHD symptoms feel more intense, leading to a further decline in mood and functioning. This overlap can sometimes delay diagnosis, as symptoms may be misattributed to either ADHD or depression alone. 

How It Helps 

Severity 

The severity of both ADHD and depression can vary, but when both conditions are present, the overall impact on an individual’s life can be profound. Treatment for major depressive disorder in ADHD typically involves a combination of medication, therapy, and lifestyle adjustments to address both conditions simultaneously. Effective management can significantly improve quality of life. 

In summary, major depressive disorder in ADHD affects a substantial proportion of ADHD patients, with diagnosis rates being high. Addressing both the severity and the interaction of these conditions is key to improving mental health outcomes. 

Visit providers like ADHD Certify for personal consultations and expert advice tailored to your needs.   

For a deeper dive into the science, diagnosis, and full treatment landscape, read our complete guide to Depression.  

Harriet Winslow, BSc - My patient advice author - mypatientadvice.co.uk

Harriet Winslow, BSc

Author

Harriet Winslow is a clinical psychologist with a Bachelor’s in Clinical Psychology and extensive experience in behaviour therapy and developmental disorders. She has worked with children and adolescents with ADHD, autism spectrum disorder (ASD), learning disabilities, and behavioural challenges, providing individual and group therapy using evidence-based approaches such as CBT and DBT. Dr. Winslow has developed and implemented personalised treatment plans, conducted formal and informal assessments, and delivered crisis intervention for clients in need of urgent mental health care. Her expertise spans assessment, treatment planning, and behavioural intervention for both neurodevelopmental and mental health conditions.

All qualifications and professional experience stated above are authentic and verified by our editorial team. However, pseudonym and image likeness are used to protect the author's privacy.

Dr. Rebecca Fernandez, MBBS, author and a reviewer for my patient advice - mypatientadvice.co.uk

Dr. Rebecca Fernandez, MBBS

Reviewer

Dr. Rebecca Fernandez is a UK-trained physician with an MBBS and experience in general surgery, cardiology, internal medicine, gynecology, intensive care, and emergency medicine. She has managed critically ill patients, stabilised acute trauma cases, and provided comprehensive inpatient and outpatient care. In psychiatry, Dr. Fernandez has worked with psychotic, mood, anxiety, and substance use disorders, applying evidence-based approaches such as CBT, ACT, and mindfulness-based therapies. Her skills span patient assessment, treatment planning, and the integration of digital health solutions to support mental well-being.

All qualifications and professional experience stated above are authentic and verified by our editorial team. However, pseudonym and image likeness are used to protect the reviewer's privacy. 

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