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Can Depression or ADHD Coexist, and How is Treatment Managed in Such Cases? 

PostedAugust 28, 2025
UpdatedSeptember 8, 2025
ByMy Patient Advice

Comorbidity of ADHD and depression is not uncommon, with many individuals experiencing both conditions simultaneously. This dual diagnosis can complicate treatment, as the symptoms of ADHD and depression can overlap, making it challenging to distinguish one from the other. However, with the right approach, both conditions can be managed effectively. 

Discover if you have ADHD

How ADHD and Depression Coexist 

When ADHD and depression co-occur, the symptoms of each disorder can exacerbate the other. For example, the impulsivity and lack of focus associated with ADHD can increase the feelings of helplessness and fatigue that are common in depression. On the other hand, low motivation and persistent negative thinking in depression can make it even harder for individuals with ADHD to stay on task or follow through with goals. 

Integrated Treatment for ADHD and Depression 

The key to treating comorbidity of ADHD and depression is an integrated treatment plan that combines both therapeutic and medical interventions. Cognitive Behavioural Therapy (CBT) is effective for managing both ADHD and depression, helping individuals develop coping strategies for time management, emotional regulation, and negative thinking patterns. Medication is also often used, with stimulants or non-stimulants for ADHD and antidepressants for depression.  

In short, the combined approach of therapy and medication ensures both conditions are treated, leading to better outcomes. 

Visit providers like ADHD Certify for personal consultations and expert guidance tailored to your unique situation. 

For a deeper dive into the science, diagnosis, and full treatment landscape, read our complete guide to Differential Diagnosis of ADHD.

Discover if you have ADHD
Avery Lombardi, MSc, author for my patient advice - mypatientadvice.co.uk

Avery Lombardi, MSc

Author

Avery Lombardi is a clinical psychologist with a Master’s in Clinical Psychology and a Bachelor’s in Psychology. She has professional experience in psychological assessment, evidence-based therapy, and research, working with both child and adult populations. Avery has provided clinical services in hospital, educational, and community settings, delivering interventions such as CBT, DBT, and tailored treatment plans for conditions including anxiety, depression, and developmental disorders. She has also contributed to research on self-stigma, self-esteem, and medication adherence in psychotic patients, and has created educational content on ADHD, treatment options, and daily coping strategies.

All qualifications and professional experience stated above are authentic and verified by our editorial team. However, pseudonym and image likeness are used to protect the author's privacy. 

Dr. Rebecca Fernandez, MBBS, author and a reviewer for my patient advice - mypatientadvice.co.uk

Dr. Rebecca Fernandez, MBBS

Reviewer

Dr. Rebecca Fernandez is a UK-trained physician with an MBBS and experience in general surgery, cardiology, internal medicine, gynecology, intensive care, and emergency medicine. She has managed critically ill patients, stabilised acute trauma cases, and provided comprehensive inpatient and outpatient care. In psychiatry, Dr. Fernandez has worked with psychotic, mood, anxiety, and substance use disorders, applying evidence-based approaches such as CBT, ACT, and mindfulness-based therapies. Her skills span patient assessment, treatment planning, and the integration of digital health solutions to support mental well-being.

All qualifications and professional experience stated above are authentic and verified by our editorial team. However, pseudonym and image likeness are used to protect the reviewer's privacy. 

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