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Is There a Genetic Link Between ADHD and Bipolar Disorder? 

PostedAugust 29, 2025
UpdatedSeptember 8, 2025
ByMy Patient Advice

The question of whether there is a link between ADHD and bipolar genetics has garnered significant interest in recent years. While both conditions have distinct symptoms, research suggests that genetics may play a role in their development, and there could be shared hereditary factors influencing both disorders. 

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ADHD Bipolar Genetics: Exploring the Connection 

Both ADHD and bipolar disorder tend to run in families, suggesting a potential hereditary link. Studies have shown that individuals with a first-degree relative (such as a parent or sibling) with ADHD or bipolar disorder are more likely to develop the condition themselves. This family history component points to a genetic predisposition that may contribute to the risk of developing both disorders. 

However, ADHD and bipolar genetics are complex and not entirely understood. The genetic overlap is thought to involve certain genes related to dopamine regulation, a neurotransmitter crucial for mood and behaviour control. Variations in dopamine receptor genes, such as DRD4 and DAT1, have been linked to ADHD, while genes affecting mood regulation and neuronal function may contribute to bipolar disorder.  

Family History and Hereditary Link 

The family history of both ADHD and bipolar disorder strengthens the theory of a genetic connection. While the exact nature of the genetic link remains uncertain, both conditions appear to have a strong hereditary component. A child with a parent who has either ADHD or bipolar disorder may have a higher likelihood of developing one or both conditions. 

In conclusion, while there is no definitive answer regarding the exact link between ADHD and bipolar genetics, growing evidence suggests shared genetic factors could contribute to both conditions. Understanding this genetic relationship is essential for further research and improved treatment strategies. 

Visit providers like ADHD Certify for personal consultations and expert guidance tailored to your unique situation. 

For a deeper dive into the science, diagnosis, and full treatment landscape, read our complete guide to Differential Diagnosis of ADHD.

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Avery Lombardi, MSc, author for my patient advice - mypatientadvice.co.uk

Avery Lombardi, MSc

Author

Avery Lombardi is a clinical psychologist with a Master’s in Clinical Psychology and a Bachelor’s in Psychology. She has professional experience in psychological assessment, evidence-based therapy, and research, working with both child and adult populations. Avery has provided clinical services in hospital, educational, and community settings, delivering interventions such as CBT, DBT, and tailored treatment plans for conditions including anxiety, depression, and developmental disorders. She has also contributed to research on self-stigma, self-esteem, and medication adherence in psychotic patients, and has created educational content on ADHD, treatment options, and daily coping strategies.

All qualifications and professional experience stated above are authentic and verified by our editorial team. However, pseudonym and image likeness are used to protect the author's privacy. 

Dr. Rebecca Fernandez, MBBS, author and a reviewer for my patient advice - mypatientadvice.co.uk

Dr. Rebecca Fernandez, MBBS

Reviewer

Dr. Rebecca Fernandez is a UK-trained physician with an MBBS and experience in general surgery, cardiology, internal medicine, gynecology, intensive care, and emergency medicine. She has managed critically ill patients, stabilised acute trauma cases, and provided comprehensive inpatient and outpatient care. In psychiatry, Dr. Fernandez has worked with psychotic, mood, anxiety, and substance use disorders, applying evidence-based approaches such as CBT, ACT, and mindfulness-based therapies. Her skills span patient assessment, treatment planning, and the integration of digital health solutions to support mental well-being.

All qualifications and professional experience stated above are authentic and verified by our editorial team. However, pseudonym and image likeness are used to protect the reviewer's privacy. 

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